Lidocaine CAS 137-58-6 and Lidocaine Hydrochloride Monohydrate or Lidocaine HCL CAS 6108-05-0

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Lidocaine CAS 137-58-6 and Lidocaine Hydrochloride Monohydrate or Lidocaine Hcl CAS 6108-05-0                                              

Product   Name:

Lidocaine

Lidocaine   Hydrochloride Monohydrate

Synonyms:

Lidocainum,   Lidocaine Base

Lidocaine   Hcl,

 Lidocaini hydrochloridum

Characteristics:

White   to almost white crystalline powder.

White   crystalline powder.

Solubility:  

Very   soluble in alcohol and in methylene chloride. Practically

insoluble   in water.

Freely   soluble in alcohol. Very soluble in water.

CAS   Number:

37-58-6

6108-05-0

Assay:

97.5%   ~ 102.5%

99%   ~ 101%

Standard:

BP,   EP, USP

BP,   EP, USP

Formula:

C14H22N2O

C14H23ClN2O,H2O

Structure:  

Package:

25Kg/Cardboard   Drum

25Kg/Cardboard   Drum

RS of Lidocaine

 

Usage:  It is the raw material to make Lidocaine and Lidocaine Hcl preparations.

For example: Lidocaine Topical Aerosol, Lidocaine Hydrochloride Injection, Lidocaine Hcl Jelly, Lidocaine Hydrochloride Oral Topical Solution.

And together with other APIs, there are Neomycin and Polymyxin B Sulfates and Lidocaine Cream.  Lidocaine and Lidocaine Hcl is mainly used to make us fell no pain. 

Certificate of Analysis: Lidocaine Base

Tests Specifications Results

Characters

White   or slightly yellow crystalline powder with characteristic odor.

Conforms

Identification

Should comply

Complies

Appearance   of solution

Clear   and colorless

Complies

Moisture

≤0.5%

0.32%

Sulphate

≤0.1%

0.058%

Chloride

≤0.0035%

≤0.0025%

Heavy   metals

≤20ppm

10ppm

Residue   on ignition

≤0.1%

0.01%

Impurity

(2,   6-dimethylaniline content)

≤0.01%

Complies

Assay(HLPC)

99.0%~101.0%

(Lidocaine)

99.8%

Conclusion:

The   product meets the specification of BP2010 Standard.

 

Certificate of Analysis: Lidocaine Hydrochloride(Hcl)

Tests Specifications Results

Characters

White   crystalline powder

Conforms

Melting   Point

74~79

75~76.5

Identification

Should comply

Complies

Appearance   of solution

Clear   and colorless

Complies

Moisture

5.5~7.0%

6.44%

Impurity

(2,   6-dimethylaniline content)

Should   Comply

Complies

Sulphated   Ash

≤0.1%

0.02%

Heavy   metals

≤5ppm

<5ppm

PH

4.0~5.5

4.6

Assay

(Lidocaine   Hydrochloride)

99.0%~101.0%

(Lidocaine   Hcl)

100%

Conclusion:

The   Product meets the specification of BP2010.